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Moxifloxacin+dexamethasone Phosphate

About Moxifloxacin+dexamethasone Phosphate

Dexamethasone Phosphate+moxifloxacin belongs to the class of antibiotic medications used to treat bacterial eye infections. It treats eye infections like conjunctivitis (infected conjunctiva) and other inflammatory conditions after eye surgery. Bacterial eye infection occurs when harmful bacteria invade any part of the eye, such as the eyeball, conjunctiva, or cornea. Symptoms of an infection include red eye, pain, discharge, watery/dry eyes, swelling, itching, and sensitivity to light. 

Dexamethasone Phosphate+moxifloxacin combines two medicines: Moxifloxacin (antibiotic) and Dexamethasone phosphate (steroid). Moxifloxacin is an antibiotic that stops bacterial replication, thereby killing and controlling the growth of bacterial infection. Dexamethasone phosphate is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation, by inhibiting prostaglandins that cause inflammation. Thus together, Dexamethasone Phosphate+moxifloxacin treats bacterial eye infections.

Use Dexamethasone Phosphate+moxifloxacin as prescribed by your doctor. The common side-effects of Dexamethasone Phosphate+moxifloxacin are application site burning/stinging sensation, redness and temporary blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Dexamethasone Phosphate+moxifloxacin if you are allergic to Moxifloxacin, Dexamethasone phosphate, or any contents in it. Before using the Dexamethasone Phosphate+moxifloxacin, inform your doctor if you have fungal infections, viral infections, herpes simplex or varicella, or parasitic infections such as amoebiasis. Do not use Dexamethasone Phosphate+moxifloxacin if you have tuberculosis, damaged cornea, ulceration, lesions with incomplete formation of the covering tissue, and increased pressure inside the eye.

Uses of Moxifloxacin+dexamethasone Phosphate

Bacterial eye infections

Medicinal Benefits

Dexamethasone Phosphate+moxifloxacin is a combination of two medicines: Moxifloxacin and Dexamethasone phosphate. Moxifloxacin is a fluoroquinolone antibiotic that interferes with the formation of essential proteins required for bacterial growth. Dexamethasone phosphate is a steroid medicine with anti-inflammatory properties and acts by inhibiting the chemicals, such as prostaglandins, that cause inflammation. It also reduces symptoms associated with infection, such as redness and irritation.

Directions for Use

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Moxifloxacin+dexamethasone Phosphate

  • Stinging or burning sensation
  • Redness 
  • Blurred vision
  • Swelling
  • Watery eyes

Drug Warnings

Before taking Dexamethasone Phosphate+moxifloxacin, inform your doctor if you have vision problems, severe pain in the eye, glaucoma (raised pressure in the eye), eye injury or eye surgery. Do not use Dexamethasone Phosphate+moxifloxacin for longer than recommended by your doctor as it may suppress adrenal gland function and increase the risk of cataracts (clouding of the eye). Dexamethasone Phosphate+moxifloxacin should not be used in conditions like herpes simplex virus infection or other viral eye infections.

Drug Interactions

Drug-Drug interactions: Dexamethasone Phosphate+moxifloxacin may interact with antiviral or anti-HIV (e.g. ritonavir, cobicistat).

Drug-Food interactions: No interactions found.

Drug-Disease interactions: Dexamethasone Phosphate+moxifloxacin should not be used in patients with fungal infections, viral infections such as herpes simplex or varicella, or parasitic infections such as amoebiasis, tuberculosis, or damaged cornea, ulceration, and glaucoma (increased pressure inside the eye).

Drug-Drug Interactions Checker List:

  • RITONAVIR
  • COBICISTAT
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is advisable not to take or limit alcohol as a precautionary measure.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor. Dexamethasone Phosphate+moxifloxacin should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Dexamethasone Phosphate+moxifloxacin should be used in breastfeeding mothers only if the benefits outweigh the risks. Please consult the doctor. Your doctor will only provide a prescription if the benefits outweigh the risks.

    • Safety Warning

      Driving

      caution

      Dexamethasone Phosphate+moxifloxacin may cause vision problems. However, it will be mild and temporary. So, it is advisable to avoid driving until your vision clears.

    • Safety Warning

      Liver

      caution

      Please consult your doctor if you have any concerns regarding using Dexamethasone Phosphate+moxifloxacin in patients with liver impairment.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor if you have any concerns regarding using Dexamethasone Phosphate+moxifloxacin in patients with kidney impairment.

    • Safety Warning

      Children

      caution

      Dexamethasone Phosphate+moxifloxacin should be used with caution in children. It is not recommended for use in newborns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Sleep for at least six to eight hours to rejuvenate your eyes naturally.
    • Wash your eyes with clean water at least two to three times a day. Do not wash your eyes for at least two weeks if you have undergone any eye surgery. 
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Avoid alcoholic beverages as they can make you dehydrated and affect your sleep. This can also affect your body’s ability to fight off infections.

    Patients Concern

    Disease/Condition Glossary

    Bacterial eye infections: Bacterial eye infection occurs when harmful bacteria invade any part of the eye, such as the eyeball, conjunctiva, or cornea. The common bacterial eye infections are conjunctivitis, stye, or keratitis. Conjunctivitis (pink eye) is the inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that is spread by eye secretions. Symptoms include redness, itchiness, and discharge or crusting around the eye. A stye is a bump on the eyelid, which is also a common eye condition. Keratitis is the inflammation of the cornea that occurs due to frequent contact lenses, injury, diabetes, or surgery.

    FAQs

    Dexamethasone Phosphate+moxifloxacin is a combination of two medicines: Moxifloxacin and Dexamethasone phosphate. Moxifloxacin stops bacterial replication, thereby killing and stopping the growth of bacterial infection. Dexamethasone phosphate reduces inflammation and symptoms associated with infection, such as redness and irritation, by inhibiting prostaglandins that cause inflammation. Thus together, Dexamethasone Phosphate+moxifloxacin treats bacterial eye infections.

    Use Dexamethasone Phosphate+moxifloxacin only for the duration recommended by your doctor. Please do not use it for more than the recommended duration as it contains dexamethasone phosphate, a steroid that can cause unwanted side effects.

    Dexamethasone Phosphate+moxifloxacin can be used with other eye medications if prescribed by the doctor. Maintain a gap of 10-15minutes between Dexamethasone Phosphate+moxifloxacin and other eye medications.

    Do not wear contact lenses while using Dexamethasone Phosphate+moxifloxacin. Remember to remove the contact lenses before using the Dexamethasone Phosphate+moxifloxacin. Using spectacles and avoiding wearing contact lenses is recommended until the infection is cleared.

    Available Medicines for

    Moxifloxacin+dexamethasone Phosphate

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